On offense, the only healthy starter I'd even consider NOT playing is Richardson... but I'd even give him 1 series
On defense, maybe keep out P.Taylor and D. Bryant if they are still recovering... Rubin, Haden, Jackson, Kruger, Ward don't play much
You want to play a quarter with Weeden, Benjamin, Little, Cameron, and the O-line. Also about a quarter for Robertson, Sheard, Gipson (if healthy), and Owens.
Hopefully all the draft picks are healthy so they can play good time to get a feel for the speed of NFL football...